Publication: Interleukin-2: biology, design and application
Date
Date
Date
2015
Journal Article
Published version
Abstract
Abstract
Abstract
Interleukin-2 (IL-2) exerts crucial functions during immune homeostasis via its effects on regulatory T (Treg) cells, and the optimizing and fine-tuning of effector lymphocyte responses. Thus, somewhat paradoxically, low doses of recombinant IL-2 have been used for Treg cell-based immunosuppressive strategies against immune pathologies, while high-dose IL-2 has shown some success in stimulating anti-tumor immune responses. Recent studies of the functional, biophysical and structural characteristics of IL-2 have led to the generation o
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4771 since deposited on 2017-02-10
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Acq. date: 2025-11-13
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2365 since deposited on 2017-02-10
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Additional indexing
Creators (Authors)
- Arenas-Ramirez, Natalia
- Woytschak, Janine
- Boyman, Onur
Volume
Volume
Volume
36
Number
Number
Number
12
Page range/Item number
Page range/Item number
Page range/Item number
763
Page end
Page end
Page end
777
Item Type
Item Type
Item Type
Journal Article
In collections
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Keywords
Interleukin-2, Biology, Design, Application
Language
Language
Language
English
Publication date
Publication date
Publication date
2015-12
Date available
Date available
Date available
2017-02-10
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
1471-4906
OA Status
OA Status
OA Status
Green
Publisher DOI
Metrics
Downloads
4771 since deposited on 2017-02-10
4744last week
Acq. date: 2025-11-13
Views
2365 since deposited on 2017-02-10
2360last week
Acq. date: 2025-11-13
Green Open Access
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