Publication: Accounting for Range Uncertainties in the Optimization of Combined Proton-Photon Treatments Via Stochastic Optimization
Accounting for Range Uncertainties in the Optimization of Combined Proton-Photon Treatments Via Stochastic Optimization
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Fabiano, S., Bangert, M., Guckenberger, M., & Unkelbach, J. (2020). Accounting for Range Uncertainties in the Optimization of Combined Proton-Photon Treatments Via Stochastic Optimization. International Journal of Radiation Oncology, Biology, Physics, 108(3), 792–801. https://doi.org/10.1016/j.ijrobp.2020.04.029
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Purpose: Proton treatment slots are a limited resource. Combined proton-photon treatments, in which most fractions are delivered with photons and only a few with protons, may represent a practical solution to optimize the allocation of proton resources over the patient population. We demonstrate how a limited number of proton fractions can be optimally used in multimodality treatments and address the issue of the robustness of combined treatments against proton range uncertainties.
Methods and materials: Combined proton-photon treatm
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- Fabiano, Silvia
- Bangert, Mark
- Guckenberger, Matthias
- Unkelbach, Jan
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Fabiano, S., Bangert, M., Guckenberger, M., & Unkelbach, J. (2020). Accounting for Range Uncertainties in the Optimization of Combined Proton-Photon Treatments Via Stochastic Optimization. International Journal of Radiation Oncology, Biology, Physics, 108(3), 792–801. https://doi.org/10.1016/j.ijrobp.2020.04.029