Publication: Immunohistochemical expression of Bax and Bak in canine non-neoplastic tissues
Immunohistochemical expression of Bax and Bak in canine non-neoplastic tissues
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Croci, M., Dettwiler, M., Vaughan, L., & Guscetti, F. (2013). Immunohistochemical expression of Bax and Bak in canine non-neoplastic tissues. Veterinary Journal, 198(1), 131–140. https://doi.org/10.1016/j.tvjl.2013.07.029
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Apoptosis is critical for embryonic development, maintenance of tissue homeostasis and protection against malignant transformation. The Bcl-2 family of proteins plays a key role in intrinsic apoptosis by controlling the integrity of the outer mitochondrial membrane, and the multidomain pro-apoptotic Bcl-2 family members Bax and Bak are essential components of this pathway. The aim of this study was to provide data on the expression of these proteins in normal canine tissues. Two antibodies against Bax recognising different conformatio
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- Croci, Martina
- Dettwiler, Martina
- Vaughan, Lloyd
- Guscetti, Franco
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Croci, M., Dettwiler, M., Vaughan, L., & Guscetti, F. (2013). Immunohistochemical expression of Bax and Bak in canine non-neoplastic tissues. Veterinary Journal, 198(1), 131–140. https://doi.org/10.1016/j.tvjl.2013.07.029
