Publication: Multicompartmental non-invasive sensing of postprandial lipemia in humans with multispectral optoacoustic tomography
Multicompartmental non-invasive sensing of postprandial lipemia in humans with multispectral optoacoustic tomography
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Fasoula, N.-A., Karlas, A., Kallmayer, M., Milik, A. B., Pelisek, J., Eckstein, H.-H., Klingenspor, M., & Ntziachristos, V. (2021). Multicompartmental non-invasive sensing of postprandial lipemia in humans with multispectral optoacoustic tomography. Molecular Metabolism, 47, 101184. https://doi.org/10.1016/j.molmet.2021.101184
Abstract
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Abstract
OBJECTIVE
Postprandial lipid profiling (PLP), a risk indicator of cardiometabolic disease, is based on frequent blood sampling over several hours after a meal, an approach that is invasive and inconvenient. Non-invasive PLP may offer an alternative for disseminated human monitoring. Herein, we investigate the use of clinical multispectral optoacoustic tomography (MSOT) for non-invasive, label-free PLP via direct lipid-sensing in human vasculature and soft tissues.
METHODS
Four (n = 4) subjects (3 females and 1 male, age: 28 ± 7 yea
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Fasoula, N.-A., Karlas, A., Kallmayer, M., Milik, A. B., Pelisek, J., Eckstein, H.-H., Klingenspor, M., & Ntziachristos, V. (2021). Multicompartmental non-invasive sensing of postprandial lipemia in humans with multispectral optoacoustic tomography. Molecular Metabolism, 47, 101184. https://doi.org/10.1016/j.molmet.2021.101184