Publication:

Bryophyllum pinnatum Inhibits Oxytocin and Vasopressin Signaling in Myometrial Cells

Date

Date

Date
2024
Journal Article
Published version

Citations

Citation copied

Zurfluh, L., Duvaud, L., Inci, N., Potterat, O., Simões-Wüst, A. P., & Mosbacher, J. (2024). Bryophyllum pinnatum Inhibits Oxytocin and Vasopressin Signaling in Myometrial Cells. Planta Medica, 90(10), 757–765. https://doi.org/10.1055/a-2303-9608

Abstract

Abstract

Abstract

The medicinal plant Bryophyllum pinnatum was previously shown to block oxytocin (OT)-induced signals in myometrial cells, consistent with its tocolytic effect observed in patients. OT activates not only OT receptors but also V1A receptors, two receptors with high receptor homology that are both expressed in the myometrium and play a crucial role in myometrial contraction signaling. We aimed to study the molecular pharmacology of B. pinnatum herbal preparations using specific receptor ligands, the human myometrial cell line hTERT-C3, a

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41 since deposited on 2024-12-18
Acq. date: 2025-11-13

Additional indexing

Creators (Authors)

  • Zurfluh, Leonie
    affiliation.icon.alt
  • Duvaud, Lauriane
    affiliation.icon.alt
  • Inci, Nejla
    affiliation.icon.alt
  • Potterat, Olivier
    affiliation.icon.alt
  • Simões-Wüst, Ana Paula
    affiliation.icon.alt
  • Mosbacher, Johannes
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
90

Number

Number

Number
10

Page range/Item number

Page range/Item number

Page range/Item number
757

Page end

Page end

Page end
765

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2024-08

Date available

Date available

Date available
2024-12-18

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
0032-0943

OA Status

OA Status

OA Status
Closed

PubMed ID

PubMed ID

PubMed ID

Metrics

Views

41 since deposited on 2024-12-18
Acq. date: 2025-11-13

Citations

Citation copied

Zurfluh, L., Duvaud, L., Inci, N., Potterat, O., Simões-Wüst, A. P., & Mosbacher, J. (2024). Bryophyllum pinnatum Inhibits Oxytocin and Vasopressin Signaling in Myometrial Cells. Planta Medica, 90(10), 757–765. https://doi.org/10.1055/a-2303-9608

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