Publication: Automated ERCC1 Immunohistochemistry in Non-small Cell Lung Cancer: Comparison of anti-ERCC1 Antibodies 8F1, D-10, and FL-297
Automated ERCC1 Immunohistochemistry in Non-small Cell Lung Cancer: Comparison of anti-ERCC1 Antibodies 8F1, D-10, and FL-297
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Arbogast, S., Behnke, S., Opitz, I., Stahel, R. A., Seifert, B., Weder, W., Moch, H., & Soltermann, A. (2011). Automated ERCC1 Immunohistochemistry in Non-small Cell Lung Cancer: Comparison of anti-ERCC1 Antibodies 8F1, D-10, and FL-297. Applied Immunohistochemistry and Molecular Morphology, 19(2), 99–105. https://doi.org/10.1097/PAI.0b013e3181f1feeb
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INTRODUCTION: The excision repair cross-complementation group 1 (ERCC1) protein is the key enzyme of the nucleotide excision repair (NER) pathway and thus a potential predictor for platinum-based chemotherapy response. We aimed for evaluating different anti-ERCC1 antibodies on formalin-fixed tumor tissue of non-small cell lung cancer patients by automated immunohistochemistry (IHC). METHODS: ERCC1 protein expression was assessed on a tissue microarray of 491 NSCLC's using 2 monoclonal mouse (Mab 8F1, Mab D-10) and 1 polyclonal rabbit
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- Arbogast, S
- Behnke, S
- Opitz, I
- Stahel, R A
- Seifert, B
- Weder, W
- Moch, H
- Soltermann, A
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Arbogast, S., Behnke, S., Opitz, I., Stahel, R. A., Seifert, B., Weder, W., Moch, H., & Soltermann, A. (2011). Automated ERCC1 Immunohistochemistry in Non-small Cell Lung Cancer: Comparison of anti-ERCC1 Antibodies 8F1, D-10, and FL-297. Applied Immunohistochemistry and Molecular Morphology, 19(2), 99–105. https://doi.org/10.1097/PAI.0b013e3181f1feeb
