Publication: A novel allele of the Arabidopsis thaliana MACPF protein CAD1 results in deregulated immune signaling
A novel allele of the Arabidopsis thaliana MACPF protein CAD1 results in deregulated immune signaling
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Holmes, D. R., Bredow, M., Thor, K., Pascetta, S. A., Sementchoukova, I., Siegel, K. R., Zipfel, C., & Monaghan, J. (2021). A novel allele of the Arabidopsis thaliana MACPF protein CAD1 results in deregulated immune signaling. Genetics, 217(4), iyab022. https://doi.org/10.1093/genetics/iyab022
Abstract
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Abstract
Immune recognition in plants is governed by two major classes of receptors: pattern recognition receptors (PRRs) and nucleotide-binding leucine-rich repeat receptors (NLRs). Located at the cell surface, PRRs bind extracellular ligands originating from microbes (indicative of “non-self”) or damaged plant cells (indicative of “infected-self”), and trigger signaling cascades to protect against infection. Located intracellularly, NLRs sense pathogen-induced physiological changes and trigger localized cell death and systemic resistance. Im
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- Holmes, Danalyn R
- Bredow, Melissa
- Thor, Kathrin
- Pascetta, Sydney A
- Sementchoukova, Irina
- Siegel, Kristen R
- Monaghan, Jacqueline
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Holmes, D. R., Bredow, M., Thor, K., Pascetta, S. A., Sementchoukova, I., Siegel, K. R., Zipfel, C., & Monaghan, J. (2021). A novel allele of the Arabidopsis thaliana MACPF protein CAD1 results in deregulated immune signaling. Genetics, 217(4), iyab022. https://doi.org/10.1093/genetics/iyab022
