Publication: Smoothelin, a new marker to determine the origin of liver fibrogenic cells
Smoothelin, a new marker to determine the origin of liver fibrogenic cells
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Lepreux, S., Guyot, C., Billet, F., Combe, C., Balabaud, C., Bioulac-Sage, P., & Desmoulière, A. (2013). Smoothelin, a new marker to determine the origin of liver fibrogenic cells. World Journal of Gastroenterology, 19(48), 9343–9350. https://doi.org/10.3748/wjg.v19.i48.9343
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AIM: To explore this hypothesis that smooth muscle cells may be capable of acquiring a myofibroblastic phenotype, we have studied the expression of smoothelin in fibrotic conditions. METHODS: Normal liver tissue (n = 3) was obtained from macroscopically normal parts of hepatectomy, taken at a distance from hemangiomas. Pathological specimens included post-burn cutaneous hypertrophic scars (n = 3), fibrotic liver tissue (n = 5), cirrhotic tissue (viral and alcoholic hepatitis) (n = 5), and hepatocellular carcinomas (n = 5). Tissue samp
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Lepreux, S., Guyot, C., Billet, F., Combe, C., Balabaud, C., Bioulac-Sage, P., & Desmoulière, A. (2013). Smoothelin, a new marker to determine the origin of liver fibrogenic cells. World Journal of Gastroenterology, 19(48), 9343–9350. https://doi.org/10.3748/wjg.v19.i48.9343