Publication: Response of routine inflammatory biomarkers and novel Pancreatic Stone Protein to inhalation injury and its interference with sepsis detection in severely burned patients
Response of routine inflammatory biomarkers and novel Pancreatic Stone Protein to inhalation injury and its interference with sepsis detection in severely burned patients
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Klein, H. J., Rittirsch, D., Buehler, P. K., Schweizer, R., Giovanoli, P., Cinelli, P., Plock, J. A., Reding, T., & Graf, R. (2021). Response of routine inflammatory biomarkers and novel Pancreatic Stone Protein to inhalation injury and its interference with sepsis detection in severely burned patients. Burns, 47(2), 338–348. https://doi.org/10.1016/j.burns.2020.04.039
Abstract
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BACKGROUND
Inhalation of thermal and chemical products of combustion evokes an immune response measurable at a systemic level. Inhalation injury related kinetics of currently available inflammatory biomarkers and novel Pancreatic Stone Protein (PSP) as well as their interference with septic events has not been addressed to literature yet.
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Analysis of the influence of inhalation injury and ARDS on biomarker kinetics (PSP, procalcitonin (PCT), C-reactive Protein (CRP), white blood cells (WBC)) in 90 patients admitted to Zuric
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Creators (Authors)
- Klein, Holger J
- Rittirsch, Daniel
- Buehler, Philipp K
- Schweizer, Riccardo
- Giovanoli, Pietro
- Cinelli, Paolo
- Plock, Jan A
- Reding, Theresia
- Graf, Rolf
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Citations
Klein, H. J., Rittirsch, D., Buehler, P. K., Schweizer, R., Giovanoli, P., Cinelli, P., Plock, J. A., Reding, T., & Graf, R. (2021). Response of routine inflammatory biomarkers and novel Pancreatic Stone Protein to inhalation injury and its interference with sepsis detection in severely burned patients. Burns, 47(2), 338–348. https://doi.org/10.1016/j.burns.2020.04.039