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Region-specific regulation of the serotonin 2A receptor expression in development and aging in postmortem human brain

Date

Date

Date
2015
Journal Article
Published version

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Marinova, Z., Monoranu, C.-M., Fetz, S., Walitza, S., & Grünblatt, E. (2015). Region-specific regulation of the serotonin 2A receptor expression in development and aging in postmortem human brain. Neuropathology and Applied Neurobiology, 41(4), 520–532. https://doi.org/10.1111/nan.12167

Abstract

Abstract

Abstract

AIMS The serotonin 2A receptor (HTR2A) is widely expressed in the brain and involved in the modulation of fear, mood, anxiety and other symptoms. HTR2A and HTR2A gene variations are implicated in depression, schizophrenia, anxiety and obsessive-compulsive disorder. To understand HTR2A signalling changes in psychiatric or neurodegenerative disorders, its normal pattern of brain expression and region specificity during development and aging needs to be clarified. The aim of the present study was to assess HTR2A expression through develo

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12 since deposited on 2014-07-23
Acq. date: 2025-11-12

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1 since deposited on 2014-07-23
Acq. date: 2025-11-12

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Creators (Authors)

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
41

Number

Number

Number
4

Page range/Item number

Page range/Item number

Page range/Item number
520

Page end

Page end

Page end
532

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2015

Date available

Date available

Date available
2014-07-23

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Publisher

Publisher

ISSN or e-ISSN

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ISSN or e-ISSN
0305-1846

Additional Information

Additional Information

Additional Information
This is the accepted version of the following article: Neuropathology and Applied Neurobiology 2014: Epub ahead of print, which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1111/nan.12167/abstract.

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OA Status

OA Status
Green

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PubMed ID

PubMed ID

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12 since deposited on 2014-07-23
Acq. date: 2025-11-12

Views

1 since deposited on 2014-07-23
Acq. date: 2025-11-12

Citations

Citation copied

Marinova, Z., Monoranu, C.-M., Fetz, S., Walitza, S., & Grünblatt, E. (2015). Region-specific regulation of the serotonin 2A receptor expression in development and aging in postmortem human brain. Neuropathology and Applied Neurobiology, 41(4), 520–532. https://doi.org/10.1111/nan.12167

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