Publication: Genetic and clinic predictors of new onset diabetes mellitus after transplantation
Genetic and clinic predictors of new onset diabetes mellitus after transplantation
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Saigi-Morgui, N., Quteineh, L., Bochud, P.-Y., Crettol, S., Kutalik, Z., Mueller, N. J., Binet, I., Van Delden, C., Steiger, J., Mohacsi, P., Dufour, J., Soccal, P. M., Pascual, M., & Eap, C. B. (2019). Genetic and clinic predictors of new onset diabetes mellitus after transplantation. Pharmacogenomics Journal, 19(1), 53–64. https://doi.org/10.1038/s41397-017-0001-5
Abstract
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Abstract
New Onset Diabetes after Transplantation (NODAT) is a frequent complication after solid organ transplantation, with higher incidence during the first year. Several clinical and genetic factors have been described as risk factors of Type 2 Diabetes (T2DM). Additionally, T2DM shares some genetic factors with NODAT. We investigated if three genetic risk scores (w-GRS) and clinical factors were associated with NODAT and how they predicted NODAT development 1 year after transplantation. In both main (n = 725) and replication (n = 156) samp
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- Saigi-Morgui, Núria
- Quteineh, Lina
- Bochud, Pierre-Yves
- Crettol, Severine
- Kutalik, Zoltán
- Mueller, Nicolas J
- Binet, Isabelle
- Van Delden, Christian
- Steiger, Jürg
- Mohacsi, Paul
- Dufour, Jean-francois
- Soccal, Paola M
- Pascual, Manuel
- Eap, Chin B
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Saigi-Morgui, N., Quteineh, L., Bochud, P.-Y., Crettol, S., Kutalik, Z., Mueller, N. J., Binet, I., Van Delden, C., Steiger, J., Mohacsi, P., Dufour, J., Soccal, P. M., Pascual, M., & Eap, C. B. (2019). Genetic and clinic predictors of new onset diabetes mellitus after transplantation. Pharmacogenomics Journal, 19(1), 53–64. https://doi.org/10.1038/s41397-017-0001-5