Publication: The Role of the Host Cytoskeleton in the Formation and Dynamics of Rotavirus Viroplasms
The Role of the Host Cytoskeleton in the Formation and Dynamics of Rotavirus Viroplasms
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Vetter, J., Lee, M., & Eichwald, C. (2024). The Role of the Host Cytoskeleton in the Formation and Dynamics of Rotavirus Viroplasms. Viruses, 16(5), 668. https://doi.org/10.3390/v16050668
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Rotavirus (RV) replicates within viroplasms, membraneless electron-dense globular cytosolic inclusions with liquid–liquid phase properties. In these structures occur the virus transcription, replication, and packaging of the virus genome in newly assembled double-layered particles. The viroplasms are composed of virus proteins (NSP2, NSP5, NSP4, VP1, VP2, VP3, and VP6), single- and double-stranded virus RNAs, and host components such as microtubules, perilipin-1, and chaperonins. The formation, coalescence, maintenance, and perinuclea
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Vetter, J., Lee, M., & Eichwald, C. (2024). The Role of the Host Cytoskeleton in the Formation and Dynamics of Rotavirus Viroplasms. Viruses, 16(5), 668. https://doi.org/10.3390/v16050668
