Publication: The STRING database in 2025: protein networks with directionality of regulation
The STRING database in 2025: protein networks with directionality of regulation
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Szklarczyk, D., Nastou, K., Koutrouli, M., Kirsch, R., Mehryary, F., Hachilif, R., Hu, D., Peluso, M. E., Huang, Q., Fang, T., Doncheva, N. T., Pyysalo, S., Bork, P., Jensen, L. J., & von Mering, C. (2025). The STRING database in 2025: protein networks with directionality of regulation. Nucleic Acids Research, 53, D730–D737. https://doi.org/10.1093/nar/gkae1113
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Proteins cooperate, regulate and bind each other to achieve their functions. Understanding the complex network of their interactions is essential for a systems-level description of cellular processes. The STRING database compiles, scores and integrates protein-protein association information drawn from experimental assays, computational predictions and prior knowledge. Its goal is to create comprehensive and objective global networks that encompass both physical and functional interactions. Additionally, STRING provides supplementary
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- Szklarczyk, Damian
- Nastou, Katerina
- Koutrouli, Mikaela
- Kirsch, Rebecca
- Mehryary, Farrokh
- Hachilif, Radja
- Hu, Dewei
- Peluso, Matteo E
- Huang, Qingyao
- Fang, Tao
- Doncheva, Nadezhda T
- Pyysalo, Sampo
- Bork, Peer
- Jensen, Lars J
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Szklarczyk, D., Nastou, K., Koutrouli, M., Kirsch, R., Mehryary, F., Hachilif, R., Hu, D., Peluso, M. E., Huang, Q., Fang, T., Doncheva, N. T., Pyysalo, S., Bork, P., Jensen, L. J., & von Mering, C. (2025). The STRING database in 2025: protein networks with directionality of regulation. Nucleic Acids Research, 53, D730–D737. https://doi.org/10.1093/nar/gkae1113
