Publication:

Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage

Date

Date

Date
2021
Journal Article
Published version

Citations

Citation copied

Fazilaty, H., Brügger, M. D., Valenta, T., Szczerba, B. M., Berkova, L., Doumpas, N., Hausmann, G., Scharl, M., & Basler, K. (2021). Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage. Cell Reports, 36(5), 109484. https://doi.org/10.1016/j.celrep.2021.109484

Abstract

Abstract

Abstract

We lack a holistic understanding of the genetic programs orchestrating embryonic colon morphogenesis and governing damage response in the adult. A window into these programs is the transcriptomes of the epithelial and mesenchymal cell populations in the colon. Performing unbiased single-cell transcriptomic analyses of the developing mouse colon at different embryonic stages (embryonic day 14.5 [E14.5], E15.5, and E18.5), we capture cellular and molecular profiles of the stages before, during, and after the appearance of crypt structur

Additional indexing

Creators (Authors)

  • Fazilaty, Hassan
    affiliation.icon.alt
  • Brügger, Michael David
    affiliation.icon.alt
  • Valenta, Tomas
    affiliation.icon.alt
  • Szczerba, Barbara M
    affiliation.icon.alt
  • Berkova, Linda
    affiliation.icon.alt
  • Doumpas, Nikolaos
    affiliation.icon.alt
  • Hausmann, George
    affiliation.icon.alt
  • Scharl, Michael
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
36

Number

Number

Number
5

Page range/Item number

Page range/Item number

Page range/Item number
109484

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Keywords

General Biochemistry, Genetics and Molecular Biology

Language

Language

Language
English

Publication date

Publication date

Publication date
2021-08-01

Date available

Date available

Date available
2021-08-27

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
2211-1247

OA Status

OA Status

OA Status
Gold

Free Access at

Free Access at

Free Access at
DOI

PubMed ID

PubMed ID

PubMed ID

Citations

Citation copied

Fazilaty, H., Brügger, M. D., Valenta, T., Szczerba, B. M., Berkova, L., Doumpas, N., Hausmann, G., Scharl, M., & Basler, K. (2021). Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage. Cell Reports, 36(5), 109484. https://doi.org/10.1016/j.celrep.2021.109484

Gold Open Access
Loading...
Thumbnail Image

Files

Files

Files
Files available to download:1

Files

Files

Files
Files available to download:1
Loading...
Thumbnail Image