Case 3.1 : Self-Experimentation in the Development of COVID-19 Vaccines

Abstract

This chapter focuses on issues relating to the rigour and quality of research in pandemic contexts, and the dissemination and publication of research findings. Research is indispensable to inform pandemic responses, including the development of new vaccines and therapeutic possibilities. While these studies are badly needed, public health emergencies present profound ethical challenges for the conduct of research. Key questions arise about whether and to what extent research designs should be adapted to pandemic contexts, including wh Show more