Fundamentals of randomized clinical trials in wound care: reporting standards

Brölmann, Fleur E; Eskes, Anne M; Sumpio, Bauer E; Mayer, Dieter O; Moore, Zena; Agren, Magnus S; Hermans, Michel; Cutting, Keith; Legemate, Dink A; Vermeulen, Hester; Ubbink, Dirk T

doi:10.1111/wrr.12087

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Brölmann, F. E., Eskes, A. M., Sumpio, B. E., Mayer, D. O., Moore, Z., Agren, M. S., Hermans, M., Cutting, K., Legemate, D. A., Vermeulen, H., & Ubbink, D. T. (2013). Fundamentals of randomized clinical trials in wound care: reporting standards. Wound Repair and Regeneration, 21(5), 641–647. https://doi.org/10.1111/wrr.12087

Abstract

In wound care research, available high-level evidence according to the evidence pyramid is rare, and is threatened by a poor study design and reporting. Without comprehensive and transparent reporting, readers will not be able to assess the strengths and limitations of the research performed. Randomized clinical trials (RCTs) are universally acknowledged as the study design of choice for comparing treatment effects. To give high-level evidence the appreciation it deserves in wound care, we propose a step-by-step reporting standard for