Publication: Microbiological aspects of an in situ model to study effects of antimicrobial agents on dental plaque ecology.
Microbiological aspects of an in situ model to study effects of antimicrobial agents on dental plaque ecology.
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Giertsen, E., Guggenheim, B., Thurnheer, T., & Gmür, R. (2000). Microbiological aspects of an in situ model to study effects of antimicrobial agents on dental plaque ecology. European Journal of Oral Sciences, 108, 403–411. https://doi.org/10.1034/j.1600-0722.2000.108005403.x
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This study validates an in situ model for ecological studies of dental plaque exposed to various antimicrobial agents with different modes of action on plaque bacteria. Eleven subjects wore two acrylic appliances, each containing two bovine enamel discs, during two 1-wk test periods. Using a split-mouth crossover design, the appliances were dipped twice daily for 1 min into water (control; treatment A), fluoride (26.3 mM NaF; B), zinc acetate (20.0 mM; C), or fluoride plus zinc acetate (D). Four of the subjects used also chlorhexidine
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Giertsen, E., Guggenheim, B., Thurnheer, T., & Gmür, R. (2000). Microbiological aspects of an in situ model to study effects of antimicrobial agents on dental plaque ecology. European Journal of Oral Sciences, 108, 403–411. https://doi.org/10.1034/j.1600-0722.2000.108005403.x