Publication: The RANKL-OPG system in clinical periodontology
The RANKL-OPG system in clinical periodontology
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Belibasakis, G. N., & Bostanci, N. (2012). The RANKL-OPG system in clinical periodontology. Journal of Clinical Periodontology, 39(3), 239–248. https://doi.org/10.1111/j.1600-051X.2011.01810.x
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BACKGROUND AND OBJECTIVES: The receptor activator of NF-κB ligand-osteoprotegerin (RANKL-OPG) bi-molecular system is the "bottle-neck" regulator of osteoclastogenesis and bone resorption, both in physiological and pathological conditions. This review aims to elaborate the current knowledge on RANKL and OPG in periodontal disease, and to evaluate their diagnostic and prognostic potential as biomarkers of the disease.
MATERIALS AND METHODS: To pursue this aim, electronic and manual searches were performed for identifying clinical and i
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Belibasakis, G. N., & Bostanci, N. (2012). The RANKL-OPG system in clinical periodontology. Journal of Clinical Periodontology, 39(3), 239–248. https://doi.org/10.1111/j.1600-051X.2011.01810.x