Publication: A thousand empirical adaptive landscapes and their navigability
A thousand empirical adaptive landscapes and their navigability
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Aguilar-Rodríguez, J., Payne, J. L., & Wagner, A. (2017). A thousand empirical adaptive landscapes and their navigability. Nature Ecology and Evolution, 1(2), 0045. https://doi.org/10.1038/s41559-016-0045
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Abstract
The adaptive landscape is an iconic metaphor that pervades evolutionary biology. It was mostly applied in theoretical models until recent years, when empirical data began to allow partial landscape reconstructions. Here, we exhaustively analyse 1,137 complete landscapes from 129 eukaryotic species, each describing the binding affinity of a transcription factor to all possible short DNA sequences. We find that the navigability of these landscapes through single mutations is intermediate to that of additive and shuffled null models, sug
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- Aguilar-Rodríguez, José
- Payne, Joshua L
- Wagner, Andreas
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Aguilar-Rodríguez, J., Payne, J. L., & Wagner, A. (2017). A thousand empirical adaptive landscapes and their navigability. Nature Ecology and Evolution, 1(2), 0045. https://doi.org/10.1038/s41559-016-0045
