PP2A-3 interacts with ACR4 and regulates formative cell division in the Arabidopsis root

Yue, Kun; Sandal, Priyanka; Williams, Elisabeth L; Murphy, Evan; Stes, Elisabeth; Nikonorova, Natalia; Ramakrishna, Priya; Czyzewicz, Nathan; Montero-Morales, Laura; Kumpf, Robert; Lin, Zhefeng; van de Cotte, Brigitte; Iqbal, Mudassar; Van Bel, Michiel; Van De Slijke, Eveline; Meyer, Matthew R; Gadeyne, Astrid; Zipfel, Cyril; De Jaeger, Geert; Van Montagu, Marc

doi:10.5167/uzh-260320

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Yue, K., Sandal, P., Williams, E. L., Murphy, E., Stes, E., Nikonorova, N., Ramakrishna, P., Czyzewicz, N., Montero-Morales, L., Kumpf, R., Lin, Z., van de Cotte, B., Iqbal, M., Van Bel, M., Van De Slijke, E., Meyer, M. R., Gadeyne, A., Zipfel, C., De Jaeger, G., … De Smet, I. (2016). PP2A-3 interacts with ACR4 and regulates formative cell division in the Arabidopsis root. Proceedings of the National Academy of Sciences of the United States of America, 113(5), 1447–1452. https://doi.org/10.1073/pnas.1525122113

Abstract

In plants, the generation of new cell types and tissues depends on coordinated and oriented formative cell divisions. The plasma membrane-localized receptor kinase ARABIDOPSIS CRINKLY 4 (ACR4) is part of a mechanism controlling formative cell divisions in the Arabidopsis root. Despite its important role in plant development, very little is known about the molecular mechanism with which ACR4 is affiliated and its network of interactions. Here, we used various complementary proteomic approaches to identify ACR4-interacting protein candi