Associations between natural physiological and supraphysiological estradiol levels and stress perception

Leeners, Brigitte; Kruger, Tillmann H C; Geraedts, Kirsten; Tronci, Enrico; Mancini, Toni; Egli, Marcel; Röblitz, Susanna; Saleh, Lanja; Spanaus, Katharina; Schippert, Cordula; Zhang, Yuanyuan; Ille, Fabian

doi:10.3389/fpsyg.2019.01296

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Leeners, B., Kruger, T. H. C., Geraedts, K., Tronci, E., Mancini, T., Egli, M., Röblitz, S., Saleh, L., Spanaus, K., Schippert, C., Zhang, Y., & Ille, F. (2019). Associations between natural physiological and supraphysiological estradiol levels and stress perception. Frontiers in Psychology, 10, 1296. https://doi.org/10.3389/fpsyg.2019.01296

Abstract

Stress is a risk factor for impaired general, mental, and reproductive health. The role of physiological and supraphysiological estradiol concentrations in stress perception and stress processing is less well understood. We, therefore, conducted a prospective observational study to investigate the association between estradiol, stress perception, and stress-related cognitive performance within serial measurements either during the natural menstrual cycle or during fertility treatment, where estradiol levels are strongly above the phys