Publication: Electrochemical control of the enzymatic polymerization of peg hydrogels: formation of spatially controlled biological microenvironments
Electrochemical control of the enzymatic polymerization of peg hydrogels: formation of spatially controlled biological microenvironments
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Milleret, V., Simona, B. R., Lienemann, P. S., Vörös, J., & Ehrbar, M. (2014). Electrochemical control of the enzymatic polymerization of peg hydrogels: formation of spatially controlled biological microenvironments. Advanced Healthcare Materials, 3(4), 508–514. https://doi.org/10.1002/adhm.201300479
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Control of pH gradient profile at the electrode-electrolyte interfaces allows the control of the enzymatic PEG-hydrogel polymerization. By tuning the solution pH, buffer capacity, and the applied current, the extent of the local inhibition and confinement of the Factor XIII-mediated polymerization of PEG are controlled. This technology opens new perspectives for the production of 3D-structured biological microenvironments.
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Milleret, V., Simona, B. R., Lienemann, P. S., Vörös, J., & Ehrbar, M. (2014). Electrochemical control of the enzymatic polymerization of peg hydrogels: formation of spatially controlled biological microenvironments. Advanced Healthcare Materials, 3(4), 508–514. https://doi.org/10.1002/adhm.201300479