Publication: Multilayers of hydrogels loaded with microparticles: a fast and simple approach for microarray manufacturing
Multilayers of hydrogels loaded with microparticles: a fast and simple approach for microarray manufacturing
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Bally, M., Vörös, J., & Takeuchi, S. (2010). Multilayers of hydrogels loaded with microparticles: a fast and simple approach for microarray manufacturing. Lab on a Chip, 10(3), 372–378. https://doi.org/10.1039/b916071j
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We present a novel and simple approach towards the creation of arrays of biomolecules for the multiplexed detection of biological interactions. Microarrays were obtained by cutting stacked layers of biofunctionalized polystyrene particle layers embedded in a permeable agarose matrix. Microparticles were therefore the vehicles for biorecognition. The three-dimensional constructs were obtained by consecutive dipping steps in a pre-gel solution. Our strategy enables the rapid manufacturing of a large number of array copies in a flexible
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- Bally, M
- Vörös, J
- Takeuchi, S
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Bally, M., Vörös, J., & Takeuchi, S. (2010). Multilayers of hydrogels loaded with microparticles: a fast and simple approach for microarray manufacturing. Lab on a Chip, 10(3), 372–378. https://doi.org/10.1039/b916071j