Publication: Neuropathology of the hippocampus in FTLD-Tau with Pick bodies: A study of the BrainNet Europe Consortium
Neuropathology of the hippocampus in FTLD-Tau with Pick bodies: A study of the BrainNet Europe Consortium
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Kovacs, G. G., Rozemuller, A. J. M., van Swieten, J. C., Gelpi, E., Majtenyi, K., Al-Sarraj, S., Troakes, C., Bódi, I., King, A., Hortobágyi, T., Esiri, M. M., Ansorge, O., Giaccone, G., Ferrer, I., Arzberger, T., Bogdanovic, N., Nilsson, T., Leisser, I., Alafuzoff, I., … Budka, H. (2013). Neuropathology of the hippocampus in FTLD-Tau with Pick bodies: A study of the BrainNet Europe Consortium. Neuropathology and Applied Neurobiology, 39(2), 166–178. https://doi.org/10.1111/j.1365-2990.2012.01272.x
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Aims: Frontotemporal lobar degeneration with Pick bodies (Pick's disease) is characterized by the presence of tau immunoreactive spherical structures in the cytoplasm of neurons. In view of confusion about the molecular pathology of Pick's disease, we aimed to evaluate the spectrum of tau pathology and concomitant neurodegeneration-associated protein depositions in the characteristically affected hippocampus. Methods: We evaluated immunoreactivity for tau (AT8, 3R, 4R), α-synuclein, TDP43, p62, and ubiquitin in the hippocampus, entorh
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- Kovacs, Gabor G
- Rozemuller, Annemieke J M
- van Swieten, John C
- Gelpi, Ellen
- Majtenyi, Katalin
- Al-Sarraj, Safa
- Troakes, Claire
- Bódi, István
- King, Andrew
- Hortobágyi, Tibor
- Esiri, Margaret M
- Ansorge, Olaf
- Giaccone, Giorgio
- Ferrer, Isidre
- Arzberger, Thomas
- Bogdanovic, Nenad
- Nilsson, Tatjana
- Leisser, Irene
- Alafuzoff, Irina
- Ironside, James W
- Kretzschmar, Hans
- Budka, Herbert
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Kovacs, G. G., Rozemuller, A. J. M., van Swieten, J. C., Gelpi, E., Majtenyi, K., Al-Sarraj, S., Troakes, C., Bódi, I., King, A., Hortobágyi, T., Esiri, M. M., Ansorge, O., Giaccone, G., Ferrer, I., Arzberger, T., Bogdanovic, N., Nilsson, T., Leisser, I., Alafuzoff, I., … Budka, H. (2013). Neuropathology of the hippocampus in FTLD-Tau with Pick bodies: A study of the BrainNet Europe Consortium. Neuropathology and Applied Neurobiology, 39(2), 166–178. https://doi.org/10.1111/j.1365-2990.2012.01272.x
