Publication: High thalamocortical theta coherence in patients with Parkinson's disease
High thalamocortical theta coherence in patients with Parkinson's disease
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Sarnthein, J., & Jeanmonod, D. (2007). High thalamocortical theta coherence in patients with Parkinson’s disease. Journal of Neuroscience, 27(1), 124–131. https://doi.org/10.1523/JNEUROSCI.2411-06.2007
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Research investigating the pathophysiology of Parkinson's disease (PD) mostly focuses on basal ganglia dysfunction. However, the main output from the basal ganglia is via the thalamus, and corticothalamic feedback constitutes the primary source of synapses in the thalamus. We therefore focus on the thalamocortical interplay. During the surgical intervention in six patients, local field potentials (LFPs) were recorded from pallidal-recipient thalamic nuclei VA and VLa. Simultaneously, EEG was recorded from several sites on the scalp. T
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Sarnthein, J., & Jeanmonod, D. (2007). High thalamocortical theta coherence in patients with Parkinson’s disease. Journal of Neuroscience, 27(1), 124–131. https://doi.org/10.1523/JNEUROSCI.2411-06.2007