Publication: Regional Fluid-Attenuated Inversion Recovery (FLAIR) at 7 Tesla correlates with amyloid beta in hippocampus and brainstem of cognitively normal elderly subjects
Regional Fluid-Attenuated Inversion Recovery (FLAIR) at 7 Tesla correlates with amyloid beta in hippocampus and brainstem of cognitively normal elderly subjects
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Schreiner, S. J., Liu, X., Gietl, A. F., Wyss, M., Steininger, S. C., Gruber, E., Treyer, V., Meier, I. B., Kälin, A. M., Leh, S. E., Buck, A., Nitsch, R. M., Pruessmann, K. P., Hock, C., & Unschuld, P. G. (2014). Regional Fluid-Attenuated Inversion Recovery (FLAIR) at 7 Tesla correlates with amyloid beta in hippocampus and brainstem of cognitively normal elderly subjects. Frontiers in Aging Neuroscience, 6:240. https://doi.org/10.3389/fnagi.2014.00240
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BACKGROUND: Accumulation of amyloid beta (Aβ) may occur during healthy aging and is a risk factor for Alzheimer Disease (AD). While individual Aβ-accumulation can be measured non-invasively using Pittsburgh Compund-B positron emission tomography (PiB-PET), Fluid-attenuated inversion recovery (FLAIR) is a Magnetic Resonance Imaging (MRI) sequence, capable of indicating heterogeneous age-related brain pathologies associated with tissue-edema. In the current study cognitively normal elderly subjects were investigated for regional correla
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- Schreiner, Simon J
- Liu, Xinyang
- Gietl, Anton F
- Wyss, Michael
- Steininger, Stefanie C
- Gruber, Esmeralda
- Meier, Irene B
- Leh, Sandra E
- Buck, Alfred
- Nitsch, Roger M
- Pruessmann, Klaas P
- Hock, Christoph
- Unschuld, Paul G
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Schreiner, S. J., Liu, X., Gietl, A. F., Wyss, M., Steininger, S. C., Gruber, E., Treyer, V., Meier, I. B., Kälin, A. M., Leh, S. E., Buck, A., Nitsch, R. M., Pruessmann, K. P., Hock, C., & Unschuld, P. G. (2014). Regional Fluid-Attenuated Inversion Recovery (FLAIR) at 7 Tesla correlates with amyloid beta in hippocampus and brainstem of cognitively normal elderly subjects. Frontiers in Aging Neuroscience, 6:240. https://doi.org/10.3389/fnagi.2014.00240
