Publication: Renal amyloid‐A amyloidosis in cats: Characterization of proteinuria and biomarker discovery, and associations with kidney histology
Renal amyloid‐A amyloidosis in cats: Characterization of proteinuria and biomarker discovery, and associations with kidney histology
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Palizzotto, C., Ferri, F., Callegari, C., Rossi, F., Manfredi, M., Carcangiu, L., Gerardi, G., Ferro, S., Cavicchioli, L., Müller, E., Weiss, M., Vogt, A., Lavatelli, F., Ricagno, S., Hurley, K., & Zini, E. (2024). Renal amyloid‐A amyloidosis in cats: Characterization of proteinuria and biomarker discovery, and associations with kidney histology. Journal of Veterinary Internal Medicine, 38(1), 205–215. https://doi.org/10.1111/jvim.16920
Abstract
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BackgroundAmyloid A (AA) amyloidosis is a protein misfolding disease arising from serum amyloid A (SAA). Systemic AA amyloidosis recently was shown to have a high prevalence in shelter cats in Italy and was associated with azotemia and proteinuria.ObjectivesInvestigate urine protein profiles and diagnostic biomarkers in cats with renal AA amyloidosis.AnimalsTwenty‐nine shelter cats.MethodsCase‐control study. Cats with renal proteinuria that died or were euthanized between 2018 and 2021 with available necropsy kidney, liver and spleen
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- Palizzotto, Carlo
- Ferri, Felippo
- Callegari, Carolina
- Rossi, Francesco
- Manfredi, Marcello
- Carcangiu, Laura
- Gerardi, Gabriele
- Ferro, Silvia
- Cavicchioli, Laura
- Müller, Elizabeth
- Weiss, Marco
- Vogt, Anne‐Catherine
- Lavatelli, Francesca
- Ricagno, Stefano
- Hurley, Karyl
- Zini, Eric
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Palizzotto, C., Ferri, F., Callegari, C., Rossi, F., Manfredi, M., Carcangiu, L., Gerardi, G., Ferro, S., Cavicchioli, L., Müller, E., Weiss, M., Vogt, A., Lavatelli, F., Ricagno, S., Hurley, K., & Zini, E. (2024). Renal amyloid‐A amyloidosis in cats: Characterization of proteinuria and biomarker discovery, and associations with kidney histology. Journal of Veterinary Internal Medicine, 38(1), 205–215. https://doi.org/10.1111/jvim.16920
