Publication: Validation of antibiotic efficacy on in vitro subgingival biofilms
Validation of antibiotic efficacy on in vitro subgingival biofilms
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Belibasakis, G. N., & Thurnheer, T. (2014). Validation of antibiotic efficacy on in vitro subgingival biofilms. Journal of Periodontology, 85, 343–348. https://doi.org/10.1902/jop.2013.130167
Abstract
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Background: Systemic antibiotics are often used as adjunctive treatment modalities for periodontal diseases. Testing of antimicrobial efficacy can be relevant only if the bacteria are in the form of biofilms rather than in planktonic state, and at concentrations of physiological relevance i.e. reachable in the periodontal pocket. The aim of the present study was to test on a multi-species in vitro biofilm model the antimicrobial efficacy of five different antibiotic schemes, at physiologically relevant concentrations. Methods: A 10-sp
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- Belibasakis, Georgios N
- Thurnheer, Thomas
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Belibasakis, G. N., & Thurnheer, T. (2014). Validation of antibiotic efficacy on in vitro subgingival biofilms. Journal of Periodontology, 85, 343–348. https://doi.org/10.1902/jop.2013.130167
