Publication: Generalized resistance to pruritogen-induced scratching in the C3H/HeJ strain
Generalized resistance to pruritogen-induced scratching in the C3H/HeJ strain
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Zhang, Y., Richter, N., König, C., Kremer, A. E., & Zimmermann, K. (2022). Generalized resistance to pruritogen-induced scratching in the C3H/HeJ strain. Frontiers in Molecular Neuroscience, 15, 934564. https://doi.org/10.3389/fnmol.2022.934564
Abstract
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Abstract
Previously the effect of the pruritogens, such as histamine and chloroquine, was tested in 11 inbred mouse strains, and this study aimed to identify resistant and sensitive strains, consistent with the observation that underlies the large variability in human populations. In the present study, we used the low responder C3H/HeJ (C3H) and the more sensitive C57BL/6J (C57) strain to find out if resistance and sensitivity to develop pruritus is restricted to only histamine and chloroquine or extends to other known pruritogens as well. We
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- Zhang, Yanbin
- Richter, Nicole
- König, Christine
- Kremer, Andreas E
- Zimmermann, Katharina
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Zhang, Y., Richter, N., König, C., Kremer, A. E., & Zimmermann, K. (2022). Generalized resistance to pruritogen-induced scratching in the C3H/HeJ strain. Frontiers in Molecular Neuroscience, 15, 934564. https://doi.org/10.3389/fnmol.2022.934564
