Publication: Antiretroviral concentration measurements as an additional tool to manage virologic failure in resource limited settings: a case control study
Antiretroviral concentration measurements as an additional tool to manage virologic failure in resource limited settings: a case control study
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Buzibye, A., Musaazi, J., von Braun, A., Nanzigu, S., Sekaggya-Wiltshire, C., Kambugu, A., Fehr, J., Lamorde, M., Gutteck, U., Muller, D., Sowinski, S., Reynolds, S. J., & Castelnuovo, B. (2019). Antiretroviral concentration measurements as an additional tool to manage virologic failure in resource limited settings: a case control study. AIDS Research and Therapy, 16(1), 39. https://doi.org/10.1186/s12981-019-0255-x
Abstract
Abstract
Abstract
BACKGROUND: Several studies demonstrate a correlation between sub-therapeutic concentrations of antiretroviral drugs and virologic failure. We examined the sensitivity, specificity and predictive values of sub-therapeutic drug levels in predicting viralogic failure. METHODS: This was a case control study with cases being samples of participants with virologic failure, and controls samples of participants with virologic suppression. We analyzed samples obtained from participants that had been on antiretroviral treatment (ART) for at le
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Creators (Authors)
- Buzibye, Allan
- Musaazi, Joseph
- von Braun, Amrei
- Nanzigu, Sarah
- Sekaggya-Wiltshire, Christine
- Kambugu, Andrew
- Fehr, Jan
- Lamorde, Mohammed
- Gutteck, Ursula
- Muller, Daniel
- Sowinski, Stefanie
- Reynolds, Steven J
- Castelnuovo, Barbara
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Buzibye, A., Musaazi, J., von Braun, A., Nanzigu, S., Sekaggya-Wiltshire, C., Kambugu, A., Fehr, J., Lamorde, M., Gutteck, U., Muller, D., Sowinski, S., Reynolds, S. J., & Castelnuovo, B. (2019). Antiretroviral concentration measurements as an additional tool to manage virologic failure in resource limited settings: a case control study. AIDS Research and Therapy, 16(1), 39. https://doi.org/10.1186/s12981-019-0255-x
