Publication: Incorporation of Drosophila CID/CENP-A and CENP-C into centromeres during early embryonic anaphase.
Incorporation of Drosophila CID/CENP-A and CENP-C into centromeres during early embryonic anaphase.
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Schuh, M., Lehner, C. F., & Heidmann, S. (2007). Incorporation of Drosophila CID/CENP-A and CENP-C into centromeres during early embryonic anaphase. Current Biology, 17(3), 237–243. https://doi.org/10.1016/j.cub.2006.11.051
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The centromere/kinetochore complex is indispensable for accurate segregation of chromosomes during cell divisions when it serves as the attachment site for spindle microtubules. Centromere identity in metazoans is believed to be governed by epigenetic mechanisms, because the highly repetitive centromeric DNA is neither sufficient nor required for specifying the assembly site of the kinetochore. A candidate for an epigenetic mark is the centromere-specific histone H3 variant CENP-A that replaces H3 in alternating blocks of chromatin ex
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- Schuh, M
- Heidmann, S
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Schuh, M., Lehner, C. F., & Heidmann, S. (2007). Incorporation of Drosophila CID/CENP-A and CENP-C into centromeres during early embryonic anaphase. Current Biology, 17(3), 237–243. https://doi.org/10.1016/j.cub.2006.11.051
