Publication: Tuberculosis: drug resistance, fitness, and strategies for global control
Tuberculosis: drug resistance, fitness, and strategies for global control
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Böttger, E. C., & Springer, B. (2008). Tuberculosis: drug resistance, fitness, and strategies for global control. European Journal of Pediatrics, 167, 141–148. https://doi.org/10.1007/s00431-007-0606-9
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Directly observed standardized short-course chemotherapy (DOTS) regimes are an effective treatment for drug susceptible tuberculosis disease. Surprisingly, DOTS has been reported to reduce the transmission of multi-drug resistant tuberculosis, and standardized short-course chemotherapy regimens with first-line agents have been found to be adequate treatments for some patients with drug resistant tuberculosis, including multi-drug resistance. These paradoxical observations and the apparent heterogeneity in treatment outcome of multi-dr
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Böttger, E. C., & Springer, B. (2008). Tuberculosis: drug resistance, fitness, and strategies for global control. European Journal of Pediatrics, 167, 141–148. https://doi.org/10.1007/s00431-007-0606-9