Publication: Light in a Heartbeat: Bond Scission by a Single Photon above 800 nm
Light in a Heartbeat: Bond Scission by a Single Photon above 800 nm
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Russo, M., Janeková, H., Meier, D., Generali, M., & Štacko, P. (2024). Light in a Heartbeat: Bond Scission by a Single Photon above 800 nm. Journal of the American Chemical Society, 146(12), 8417–8424. https://doi.org/10.1021/jacs.3c14197
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Photocages enable scientists to take full control over the activity of molecules using light as a biocompatible stimulus. Their emerging applications in photoactivated therapies call for efficient uncaging in the near-infrared (NIR) window, which represents a fundamental challenge. Here, we report synthetically accessible cyanine photocages that liberate alcohol, phenol, amine, and thiol payloads upon irradiation with NIR light up to 820 nm in aqueous media. The photocages display a unique chameleon-like behavior and operate via two d
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Russo, M., Janeková, H., Meier, D., Generali, M., & Štacko, P. (2024). Light in a Heartbeat: Bond Scission by a Single Photon above 800 nm. Journal of the American Chemical Society, 146(12), 8417–8424. https://doi.org/10.1021/jacs.3c14197