Publication: Mutations modulating Raf signaling in Drosophila eye development.
Mutations modulating Raf signaling in Drosophila eye development.
Date
Date
Date
Citations
Dickson, B. J., van der Straten, A., Dominguez, M., & Hafen, E. (1996). Mutations modulating Raf signaling in Drosophila eye development. Genetics, 142(1), 163–171.
Abstract
Abstract
Abstract
The R7 fate is specified during Drosophila eye development by an inductive signal transduced intracellularly via the Raf kinase. We have performed a genetic screen for dominant mutations that alter the efficiency with which cells respond to a constitutively activated Raf kinase. Such mutations may affect genes involved in signal transduction downstream of Raf. We have isolated 44 mutations that define eight genes. One of these encodes a mitogen-activated protein kinase homologue: another is a putative target gene of this signaling pat
Additional indexing
Creators (Authors)
- Dickson, B J
- van der Straten, A
- Dominguez, M
- Hafen, E
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Citations
Dickson, B. J., van der Straten, A., Dominguez, M., & Hafen, E. (1996). Mutations modulating Raf signaling in Drosophila eye development. Genetics, 142(1), 163–171.
