Publication: Effects of Polydeoxyribonucleotide (PDRN) on Endosinus Bone Regeneration Following Sinus Floor Elevation: An Experimental In Vivo Pilot Study
Effects of Polydeoxyribonucleotide (PDRN) on Endosinus Bone Regeneration Following Sinus Floor Elevation: An Experimental In Vivo Pilot Study
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Lim, H., Hong, J.-Y., Shin, S.-I., Chung, J.-H., Thoma, D. S., Jung, R. E., & Lim, H.-C. (2025). Effects of Polydeoxyribonucleotide (PDRN) on Endosinus Bone Regeneration Following Sinus Floor Elevation: An Experimental In Vivo Pilot Study. Clinical Oral Implants Research, 36(2), 239–249. https://doi.org/10.1111/clr.14378
Abstract
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OBJECTIVE To determine the effect of polydeoxyribonucleotide (PDRN) on endosinus bone regeneration in a rabbit sinus model at sequential healing time points.
MATERIALS AND METHODS Eighteen New Zealand white rabbits were used. Bilateral sinus floor elevation (SFE) was performed. Two groups were randomly assigned to each sinus: (1) test group, in which SFE was performed using collagenated bone substitute material soaked with PDRN (concentration 2.0 mg/mL, dose 0.5 mL), and (2) control group, in which SFE was performed using collagenate
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Creators (Authors)
- Lim, Hyunwoo
- Hong, Ji-Youn
- Shin, Seung-Il
- Chung, Jong-Hyuk
- Thoma, Daniel S
- Jung, Ronald E
- Lim, Hyun-Chang
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Lim, H., Hong, J.-Y., Shin, S.-I., Chung, J.-H., Thoma, D. S., Jung, R. E., & Lim, H.-C. (2025). Effects of Polydeoxyribonucleotide (PDRN) on Endosinus Bone Regeneration Following Sinus Floor Elevation: An Experimental In Vivo Pilot Study. Clinical Oral Implants Research, 36(2), 239–249. https://doi.org/10.1111/clr.14378
