Publication: Stromal Expression of Activated Leukocyte Cell Adhesion Molecule Promotes Lung Tumor Growth and Metastasis
Stromal Expression of Activated Leukocyte Cell Adhesion Molecule Promotes Lung Tumor Growth and Metastasis
Date
Date
Date
Citations
Willrodt, A.-H., Beffinger, M., Vranova, M., Protsyuk, D., Schuler, K., Jadhav, M., Heikenwalder, M., van den Broek, M., Borsig, L., & Halin, C. (2017). Stromal Expression of Activated Leukocyte Cell Adhesion Molecule Promotes Lung Tumor Growth and Metastasis. American Journal of Pathology, 187(11), 2558–2569. https://doi.org/10.1016/j.ajpath.2017.07.008
Abstract
Abstract
Abstract
Activated leukocyte cell adhesion molecule (ALCAM) is expressed on various cell types, including leukocytes, endothelial cells, and certain tumor cells. Although ALCAM expression on tumor cells has been linked to tumor invasion and metastatic spread, the contribution of ALCAM expressed in cells forming the tumor stroma to cancer progression has not been investigated. In this study, ALCAM-deficient (ALCAM-/-) mice were used to evaluate the role of ALCAM in lung tumor growth and metastasis. ALCAM-/- mice displayed an altered blood vascu
Metrics
Downloads
Views
Additional indexing
Creators (Authors)
- Willrodt, Ann-Helen
- Beffinger, Michal
- Vranova, Martina
- Protsyuk, Darya
- Schuler, Katja
- Jadhav, Maria
- Heikenwalder, Mathias
- Borsig, Lubor
- Halin, Cornelia
Volume
Volume
Volume
Number
Number
Number
Page range/Item number
Page range/Item number
Page range/Item number
Page end
Page end
Page end
Item Type
Item Type
Item Type
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Keywords
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Free Access at
Free Access at
Free Access at
Publisher DOI
Official URL
Official URL
Official URL
Metrics
Downloads
Views
Citations
Willrodt, A.-H., Beffinger, M., Vranova, M., Protsyuk, D., Schuler, K., Jadhav, M., Heikenwalder, M., van den Broek, M., Borsig, L., & Halin, C. (2017). Stromal Expression of Activated Leukocyte Cell Adhesion Molecule Promotes Lung Tumor Growth and Metastasis. American Journal of Pathology, 187(11), 2558–2569. https://doi.org/10.1016/j.ajpath.2017.07.008
