Publication: Deficient prefrontal-amygdalar connectivity underlies inefficient face processing in adolescent major depressive disorder
Deficient prefrontal-amygdalar connectivity underlies inefficient face processing in adolescent major depressive disorder
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Willinger, D., Karipidis, I. I., Häberling, I., Berger, G., Walitza, S., & Brem, S. (2022). Deficient prefrontal-amygdalar connectivity underlies inefficient face processing in adolescent major depressive disorder. Translational Psychiatry, 12, 195. https://doi.org/10.1038/s41398-022-01955-5
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Adolescence represents a critical developmental period where the prevalence of major depressive disorder (MDD) increases. Aberrant emotion processing is a core feature of adolescent MDD that has been associated with functional alterations within the prefrontal-amygdala circuitry. In this study, we tested cognitive and neural mechanisms of emotional face processing in adolescents with MDD utilizing a combination of computational modeling and neuroimaging. Thirty adolescents with MDD (age: M = 16.1 SD = 1.4, 20 females) and 33 healthy c
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Willinger, D., Karipidis, I. I., Häberling, I., Berger, G., Walitza, S., & Brem, S. (2022). Deficient prefrontal-amygdalar connectivity underlies inefficient face processing in adolescent major depressive disorder. Translational Psychiatry, 12, 195. https://doi.org/10.1038/s41398-022-01955-5