Publication: Hair glucocorticoids as biomarker for endogenous Cushing's syndrome: validation in two independent cohorts
Hair glucocorticoids as biomarker for endogenous Cushing's syndrome: validation in two independent cohorts
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Savas, M., Wester, V. L., de Rijke, Y. B., Rubinstein, G., Zopp, S., Dorst, K., van den Berg, S. A. A., Beuschlein, F., Feelders, R. A., Reincke, M., & van Rossum, E. F. C. (2019). Hair glucocorticoids as biomarker for endogenous Cushing’s syndrome: validation in two independent cohorts. Neuroendocrinology, 109(2), 171–178. https://doi.org/10.1159/000498886
Abstract
Abstract
Abstract
Background/Aims: The current diagnostic workup of Cushing’s syndrome (CS) requires various tests which only capture short-term cortisol exposure, whereas patients with endogenous CS generally have elevated long-term cortisol levels. Scalp hair assessment has emerged as a convenient test in capturing glucocorticoid concentrations over long periods of time. The aim of this multicenter, multinational, prospective, case-control study was to evaluate the diagnostic efficacy of scalp hair glucocorticoids in screening of endogenous CS. Metho
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Creators (Authors)
- Savas, Mesut
- Wester, Vincent L
- de Rijke, Yolanda B
- Rubinstein, German
- Zopp, Stephanie
- Dorst, Kristien
- van den Berg, Sjoerd A A
- Beuschlein, Felix
- Feelders, Richard A
- Reincke, Martin
- van Rossum, Elisabeth F C
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Citations
Savas, M., Wester, V. L., de Rijke, Y. B., Rubinstein, G., Zopp, S., Dorst, K., van den Berg, S. A. A., Beuschlein, F., Feelders, R. A., Reincke, M., & van Rossum, E. F. C. (2019). Hair glucocorticoids as biomarker for endogenous Cushing’s syndrome: validation in two independent cohorts. Neuroendocrinology, 109(2), 171–178. https://doi.org/10.1159/000498886
