Publication: In Vitro Gut Modeling as a Tool for Adaptive Evolutionary Engineering of Lactiplantibacillus plantarum
In Vitro Gut Modeling as a Tool for Adaptive Evolutionary Engineering of Lactiplantibacillus plantarum
Date
Date
Date
Citations
Isenring, J., Geirnaert, A., Hall, A. R., Jans, C., Lacroix, C., & Stevens, M. J. A. (2021). In Vitro Gut Modeling as a Tool for Adaptive Evolutionary Engineering of Lactiplantibacillus plantarum. MSystems, 6(2), 01085–20. https://doi.org/10.1128/msystems.01085-20
Abstract
Abstract
Abstract
Research and marketing of probiotics demand holistic strain improvement considering both the biotic and abiotic gut environment. Here, we aim to establish the continuous in vitro colonic fermentation model PolyFermS as a tool for adaptive evolutionary engineering. Immobilized fecal microbiota from adult donors were steadily cultivated up to 72 days in PolyFermS reactors, providing a long-term compositional and functional stable ecosystem akin to the donor’s gut. Inoculation of the gut microbiota with immobilized or planktonic Lactipla
Metrics
Downloads
Views
Additional indexing
Creators (Authors)
- Isenring, Julia
- Geirnaert, Annelies
- Hall, Alex R
- Jans, Christoph
- Lacroix, Christophe
- Stevens, Marc J A
Volume
Volume
Volume
Number
Number
Number
Page range/Item number
Page range/Item number
Page range/Item number
Page end
Page end
Page end
Item Type
Item Type
Item Type
In collections
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Keywords
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Free Access at
Free Access at
Free Access at
Publisher DOI
Metrics
Downloads
Views
Citations
Isenring, J., Geirnaert, A., Hall, A. R., Jans, C., Lacroix, C., & Stevens, M. J. A. (2021). In Vitro Gut Modeling as a Tool for Adaptive Evolutionary Engineering of Lactiplantibacillus plantarum. MSystems, 6(2), 01085–20. https://doi.org/10.1128/msystems.01085-20
