Publication: Microglial ‘fat shaming’ in development and disease
Microglial ‘fat shaming’ in development and disease
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Zareba, J., & Peri, F. (2021). Microglial ‘fat shaming’ in development and disease. Current Opinion in Cell Biology, 73, 105–109. https://doi.org/10.1016/j.ceb.2021.07.007
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Neuronal-immune interactions are known to play crucial roles in brain development and homoeostasis. Of great relevance in this context are microglia, brain macrophages that phagocytose neurons that die during development, and many neurological disorders. Single-cell RNA sequencing methods have significantly advanced our understanding of microglial heterogeneity and transcriptional response to environmental changes. Here, we review recent work showing how microglia adopt a similar molecular signature during development and disease char
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Zareba, J., & Peri, F. (2021). Microglial ‘fat shaming’ in development and disease. Current Opinion in Cell Biology, 73, 105–109. https://doi.org/10.1016/j.ceb.2021.07.007