Strontium hydroxyapatite in situ gel-forming system - a new approach for minimally invasive bone augmentation

Hao, J; Chou, J; Kuroda, S; Otsuka, M; Kasugai, S; Lang, N P

doi:10.1111/clr.12446

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Hao, J., Chou, J., Kuroda, S., Otsuka, M., Kasugai, S., & Lang, N. P. (2015). Strontium hydroxyapatite in situ gel-forming system - a new approach for minimally invasive bone augmentation. Clinical Oral Implants Research, 26(5), 581–585. https://doi.org/10.1111/clr.12446

Abstract

OBJECTIVES To achieve ideal functional and aesthetic requirements, ridge augmentation is often required before dental implant placement. Bone augmentation (especially vertical), which normally consists of complex and invasive surgeries, still remains challenge. This study seeks to investigate the feasibility of an injectable in situ gel-forming system containing strontium hydroxyapatite (SrHA) and alginate for minimally invasive bone augmentation in a rat calvarial model. MATERIAL AND METHODS SrHA-alginate solution was prepared by