Publication: Drosophila dany is essential for transcriptional control and nuclear architecture in spermatocytes
Drosophila dany is essential for transcriptional control and nuclear architecture in spermatocytes
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Trost, M., Blattner, A. C., Leo, S., & Lehner, C. F. (2016). Drosophila dany is essential for transcriptional control and nuclear architecture in spermatocytes. Development, 143(14), 2664–2676. https://doi.org/10.1242/dev.134759
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The terminal differentiation of adult stem cell progeny depends on transcriptional control. A dramatic change in gene expression programs accompanies the transition from proliferating spermatogonia to postmitotic spermatocytes, which prepare for meiosis and subsequent spermiogenesis. More than a thousand spermatocyte-specific genes are transcriptionally activated in early Drosophila spermatocytes. Here we describe the identification and initial characterization of dany, a gene required in spermatocytes for the large-scale change in ge
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Trost, M., Blattner, A. C., Leo, S., & Lehner, C. F. (2016). Drosophila dany is essential for transcriptional control and nuclear architecture in spermatocytes. Development, 143(14), 2664–2676. https://doi.org/10.1242/dev.134759