Publication:

No benefit from combining HE4 and CA125 as ovarian tumor markers in a clinical setting

Date

Date

Date
2011
Journal Article
Published version

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Jacob, F., Meier, M., Caduff, R., Goldstein, D., Pochechueva, T., Hacker, N., Fink, D., & Heinzelmann-Schwarz, V. (2011). No benefit from combining HE4 and CA125 as ovarian tumor markers in a clinical setting. Gynecologic Oncology, 121(3), 487–491. https://doi.org/10.1016/j.ygyno.2011.02.022

Abstract

Abstract

Abstract

OBJECTIVE: About 70% of epithelial ovarian cancer patients (EOC) are diagnosed at advanced stage with a five-year survival rate of only 30%. Whilst CA125 detects peritoneally-spread disease, it has limited sensitivity for early cancers, many of which are potentially curable. METHODS: We compared the new commercially available tumor marker HE4 with CA125 individually, in combination, within the risk of malignancy index (RMI) and the newly defined risk of malignancy algorithm (ROMA). Our prospectively-collected cohort of 160 patients co

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Creators (Authors)

  • Jacob, F
    affiliation.icon.alt
  • Meier, M
    affiliation.icon.alt
  • Caduff, R
    affiliation.icon.alt
  • Goldstein, D
    affiliation.icon.alt
  • Pochechueva, T
    affiliation.icon.alt
  • Hacker, N
    affiliation.icon.alt
  • Fink, D
    affiliation.icon.alt
  • Heinzelmann-Schwarz, V
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title
Gynecologic Oncology

Volume

Volume

Volume
121

Number

Number

Number
3

Page Range

Page Range

Page Range
487

Page end

Page end

Page end
491

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2011

Date available

Date available

Date available
2012-01-21

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
0090-8258

OA Status

OA Status

OA Status
Closed

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PubMed ID

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Jacob, F., Meier, M., Caduff, R., Goldstein, D., Pochechueva, T., Hacker, N., Fink, D., & Heinzelmann-Schwarz, V. (2011). No benefit from combining HE4 and CA125 as ovarian tumor markers in a clinical setting. Gynecologic Oncology, 121(3), 487–491. https://doi.org/10.1016/j.ygyno.2011.02.022

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