Publication: Exploiting teeth as a model to study basic features of signaling pathways
Exploiting teeth as a model to study basic features of signaling pathways
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Pagella, P., Porcheri, C., & Mitsiadis, T. A. (2020). Exploiting teeth as a model to study basic features of signaling pathways. Biochemical Society Transactions, 48, 2729–2742. https://doi.org/10.1042/bst20200514
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Teeth constitute a classical model for the study of signaling pathways and their roles in mediating interactions between cells and tissues in organ development, homeostasis and regeneration. Rodent teeth are mostly used as experimental models. Rodent molars have proved fundamental in the study of epithelial–mesenchymal interactions and embryonic organ morphogenesis, as well as to faithfully model human diseases affecting dental tissues. The continuously growing rodent incisor is an excellent tool for the investigation of the mechanism
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- Pagella, Pierfrancesco
- Porcheri, Cristina
- Mitsiadis, Thimios A
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Pagella, P., Porcheri, C., & Mitsiadis, T. A. (2020). Exploiting teeth as a model to study basic features of signaling pathways. Biochemical Society Transactions, 48, 2729–2742. https://doi.org/10.1042/bst20200514
