Publication: Hemoglobin mass and intravascular volume kinetics during and after exposure to 3,454-m altitude
Hemoglobin mass and intravascular volume kinetics during and after exposure to 3,454-m altitude
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Siebenmann, C., Cathomen, A., Hug, M., Keiser, S., Lundby, A. K., Hilty, M. P., Goetze, J. P., Rasmussen, P., & Lundby, C. (2015). Hemoglobin mass and intravascular volume kinetics during and after exposure to 3,454-m altitude. Journal of Applied Physiology, 119(10), 1194–1201. https://doi.org/10.1152/japplphysiol.01121.2014
Abstract
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High altitude (HA) exposure facilitates a rapid contraction of plasma volume (PV) and a slower occurring expansion of hemoglobin mass (Hbmass). The kinetics of the Hbmass expansion has never been examined by multiple repeated measurements, and this was our primary study aim. The second aim was to investigate the mechanisms mediating the PV contraction. Nine healthy, normally trained sea-level (SL) residents (8 males, 1 female) sojourned for 28 days at 3,454 m. Hbmass was measured and PV was estimated by carbon monoxide rebreathing at
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- Siebenmann, C
- Cathomen, A
- Hug, M
- Keiser, S
- Lundby, A K
- Hilty, M P
- Goetze, J P
- Rasmussen, P
- Lundby, C
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Siebenmann, C., Cathomen, A., Hug, M., Keiser, S., Lundby, A. K., Hilty, M. P., Goetze, J. P., Rasmussen, P., & Lundby, C. (2015). Hemoglobin mass and intravascular volume kinetics during and after exposure to 3,454-m altitude. Journal of Applied Physiology, 119(10), 1194–1201. https://doi.org/10.1152/japplphysiol.01121.2014
