Publication: A new framework for advancing in drug-induced liver injury research: The Prospective European DILI Registry
A new framework for advancing in drug-induced liver injury research: The Prospective European DILI Registry
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Björnsson, E. S., Stephens, C., Atallah, E., Robles-Diaz, M., Alvarez-Alvarez, I., Gerbes, A., Weber, S., Stirnimann, G., Kullak-Ublick, G., Cortez‐Pinto, H., Grove, J. I., Lucena, M. I., Andrade, R. J., & Aithal, G. P. (2023). A new framework for advancing in drug-induced liver injury research: The Prospective European DILI Registry. Liver International, 43(1), 115–126. https://doi.org/10.1111/liv.15378
Abstract
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Abstract
Background & aims: No multi-national prospective study of drug-induced liver injury (DILI) has originated in Europe. The design of a prospective European DILI registry, clinical features and short-term outcomes of the cases and controls is reported.
Methods: Patients with suspected DILI were prospectively enrolled in the United Kingdom, Spain, Germany, Switzerland, Portugal and Iceland, 2016-2021. DILI cases or non-DILI acute liver injury controls following causality assessment were enrolled.
Results: Of 446 adjudicated patients, 24
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Björnsson, E. S., Stephens, C., Atallah, E., Robles-Diaz, M., Alvarez-Alvarez, I., Gerbes, A., Weber, S., Stirnimann, G., Kullak-Ublick, G., Cortez‐Pinto, H., Grove, J. I., Lucena, M. I., Andrade, R. J., & Aithal, G. P. (2023). A new framework for advancing in drug-induced liver injury research: The Prospective European DILI Registry. Liver International, 43(1), 115–126. https://doi.org/10.1111/liv.15378