Publication:

Protocol for a Wnt reporter assay to measure its activity in human neural stem cells derived from induced pluripotent stem cells

Date

Date

Date
2023
Journal Article
Published version

Citations

Citation copied

Yde Ohki, C. M., Walter, N. M., Rickli, M., Salazar Campos, J. M., Werling, A. M., Döring, C., Walitza, S., & Grünblatt, E. (2023). Protocol for a Wnt reporter assay to measure its activity in human neural stem cells derived from induced pluripotent stem cells. Current Research in Neurobiology, 5, 100095. https://doi.org/10.1016/j.crneur.2023.100095

Abstract

Abstract

Abstract

The canonical Wnt signaling is an essential pathway that regulates cellular proliferation, maturation, and differentiation during neurodevelopment and maintenance of adult tissue homeostasis. This pathway has been implicated with the pathophysiology of neuropsychiatric disorders and was associated with cognitive processes, such as learning and memory. However, the molecular investigation of the Wnt signaling in functional human neural cell lines might be challenging since brain biopsies are not possible and animal models may not repre

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33 since deposited on 2023-07-14
Acq. date: 2025-11-12

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64 since deposited on 2023-07-14
Acq. date: 2025-11-12

Additional indexing

Creators (Authors)

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
5

Page range/Item number

Page range/Item number

Page range/Item number
100095

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Keywords

Human stem cells, Induced pluripotent stem cells, Neural stem cells, Neuropsychiatry, Reporter assay, Wnt signaling.

Language

Language

Language
English

Publication date

Publication date

Publication date
2023-06-17

Date available

Date available

Date available
2023-07-14

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
2665-945X

OA Status

OA Status

OA Status
Gold

Free Access at

Free Access at

Free Access at
DOI

PubMed ID

PubMed ID

PubMed ID

Metrics

Downloads

33 since deposited on 2023-07-14
Acq. date: 2025-11-12

Views

64 since deposited on 2023-07-14
Acq. date: 2025-11-12

Citations

Citation copied

Yde Ohki, C. M., Walter, N. M., Rickli, M., Salazar Campos, J. M., Werling, A. M., Döring, C., Walitza, S., & Grünblatt, E. (2023). Protocol for a Wnt reporter assay to measure its activity in human neural stem cells derived from induced pluripotent stem cells. Current Research in Neurobiology, 5, 100095. https://doi.org/10.1016/j.crneur.2023.100095

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