Publication: De novo genome sequencing and comparative stage-specific transcriptomic analysis of Dirofilaria repens
De novo genome sequencing and comparative stage-specific transcriptomic analysis of Dirofilaria repens
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Cafarelli, C., Russo, G., Mathis, A., & Silaghi, C. (2019). De novo genome sequencing and comparative stage-specific transcriptomic analysis of Dirofilaria repens. International Journal for Parasitology, 49(12), 911–919. https://doi.org/10.1016/j.ijpara.2019.04.008
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The zoonotic mosquito-borne filarial nematode Dirofilaria repens causes subcutaneous and ocular infections in dogs, cats and humans. From infected vertebrate hosts, microfilariae are taken up by mosquitoes and develop into infective L3. These are transmitted to new vertebrate hosts and develop over two further moults to adult worms. The aims of the project were (i) the de novo sequencing and annotation of the D. repens genome and (ii) comparative transcriptomic analyses of the two developmental stages, mf and L3. Genomic DNA was obtai
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- Cafarelli, Chiara
- Russo, Giancarlo
- Silaghi, Cornelia
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Cafarelli, C., Russo, G., Mathis, A., & Silaghi, C. (2019). De novo genome sequencing and comparative stage-specific transcriptomic analysis of Dirofilaria repens. International Journal for Parasitology, 49(12), 911–919. https://doi.org/10.1016/j.ijpara.2019.04.008
