Publication: Alpha-defensin lateral flow test does not appear to be useful in predicting shoulder periprosthetic joint infections
Alpha-defensin lateral flow test does not appear to be useful in predicting shoulder periprosthetic joint infections
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Weigelt, L., Plate, A., Stadler, L., Sutter, R., Frustaci, D., Zbinden, R., Zingg, P. O., Gerber, C., & Achermann, Y. (2020). Alpha-defensin lateral flow test does not appear to be useful in predicting shoulder periprosthetic joint infections. International Orthopaedics, 44(6), 1023–1029. https://doi.org/10.1007/s00264-020-04532-x
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PURPOSE: Periprosthetic joint infections (PJIs) remain a challenging complication after shoulder arthroplasty. The antimicrobial peptide α-defensin has been proposed as a new synovial fluid biomarker in diagnosing PJIs. To date, only little data are available on the diagnostic accuracy of α-defensin in shoulder PJIs; thus, we aimed to evaluate its diagnostic value in a cohort of patients with a suspected shoulder PJI. METHODS: Between June 2016 and June 2018, we prospectively enrolled patients with a diagnostic shoulder aspiration due
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- Weigelt, Lizzy
- Plate, Andreas
- Stadler, Laura
- Sutter, Reto
- Frustaci, Dario
- Zbinden, Reinhard
- Zingg, Patrick O
- Gerber, Christian
- Achermann, Yvonne
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Weigelt, L., Plate, A., Stadler, L., Sutter, R., Frustaci, D., Zbinden, R., Zingg, P. O., Gerber, C., & Achermann, Y. (2020). Alpha-defensin lateral flow test does not appear to be useful in predicting shoulder periprosthetic joint infections. International Orthopaedics, 44(6), 1023–1029. https://doi.org/10.1007/s00264-020-04532-x
