Publication: Signatures of Discriminative Copy Number Aberrations in 31 Cancer Subtypes
Signatures of Discriminative Copy Number Aberrations in 31 Cancer Subtypes
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Gao, B., & Baudis, M. (2021). Signatures of Discriminative Copy Number Aberrations in 31 Cancer Subtypes. Frontiers in Genetics, 12, 654887. https://doi.org/10.3389/fgene.2021.654887
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Copy number aberrations (CNA) are one of the most important classes of genomic mutations related to oncogenetic effects. In the past three decades, a vast amount of CNA data has been generated by molecular-cytogenetic and genome sequencing based methods. While this data has been instrumental in the identification of cancer-related genes and promoted research into the relation between CNA and histo-pathologically defined cancer types, the heterogeneity of source data and derived CNV profiles pose great challenges for data integration a
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Gao, B., & Baudis, M. (2021). Signatures of Discriminative Copy Number Aberrations in 31 Cancer Subtypes. Frontiers in Genetics, 12, 654887. https://doi.org/10.3389/fgene.2021.654887